Objective To study the bone remodeling behavior under different damage situations. Methods In this paper, a bone remodeling model under the action of fatigue mechanism was proposed. By establishing a three-dimensional finite element model of the proximal femur and combining with the finite element method, the bone remodeling under three loading conditions was simulated, and the mechanical properties and density changes of the proximal femur were analyzed. Results The damage increased by increasing the number of loading cycles. Under different damage conditions, bone showed different remodeling behaviors. As a repair mechanism, bone remodeling can make up for the loss of bone mass due to fatigue damage within a certain range. Conclusions The damage adaptive remodeling model proposed in this paper can simulate the bone remodeling behavior under different damage amount, and the overload absorption caused by excessive loading cycles. The study on the behavior of bone remodeling under the fatigue damage can provide reference for fracture prevention and theoretical basis for postoperative rehabilitation treatment.