Objective Currently, the clinical classification of severity of renal artery stenosis (RAS) solely depends on the stenosis degree, ignoring additional important morphological parameters, which may lead to errors when planning clinical treatment to patients. Method This study uses computational fluid dynamics (CFD) to explore the hemodynamic effects of stenosis area (AS), symmetry, length and shape on the renal artery following stenosis development. Idealized abdominal aorta models with main branches including narrow renal arteries were created. The area, symmetry, length and shape of stenosis were analyzed in four separate parametric studies. Results In this study, it was found that renal perfusion, pressure drop and wall shear stress distribution in renal artery stenosis were significantly correlated with stenosis area. When the stenosis area was greater than 70%, all hemodynamic parameters changed significantly. In addition, the symmetry of stenosis had obvious effect on the reflux area after renal artery stenosis, but the length and shape of stenosis had little effect on the hemodynamics of renal artery. Conclusion Although AS is still the most significant influencing factor in RAS, other morphological parameters, especially asymmetric stenosis, can not be neglected. Therefore, clinical treatment plans should be a comprehensive evaluation based on these morphological parameters.