Objective In view of the loss of control of micro-miniature unmanned aerial vehicles and various accidents in recent years, in order to evaluate the damage caused by accidental uncontrolled fall of the micro-miniature unmanned aerial vehicles to the human body, especially the head. Methods The ABAQUS dynamics numerical simulation analysis firstly simplifies the modeling of the human head and neck through the mass-spring system, based on the existing human biological tissue performance parameters. I model the human head through the scalp slab details, and then select the total weight of 6 kg. The unmanned aerial vehicles simplified by different geometries are free to fall and hit the human head, and I analyze the degree of damage caused by the falling impact on the human head. Results For the unmanned aerial vehicles falling from 10 m with a weight of 0.5 kg, the AIS values of the simplified disc impact were 1.04, and the AIS values of the spherical and conical were 1.95 and 2.48. Conclusions When the unmanned aerial vehicle with the same geometry hits the human head, the mass and the fall height increase, and the head impact acceleration and the AIS values increase linearly. When the unmanned aerial vehicles is simplified to a disk, AIS values can be fitted as a first-order function( ). When the unmanned aerial vehicles hits the human head at different angles, the unmanned aerial vehicles simplified into a disc has the smallest impact acceleration and AIS values and minimal damage. If the unmanned aerial vehicles simplified into a sphere and a cone, the impact acceleration and AIS values are less different, but the damage degree is large, which should be paid attention to in the rescue and emergency treatment of human damage.