周海宇,李元超,王成焘.力学参数随深度变化的关节软骨数值模拟[J].医用生物力学,2011,26(2):168-172
力学参数随深度变化的关节软骨数值模拟
Articular cartilage simulation using depth-dependent mechanical parameters
投稿时间:2010-12-06  修订日期:2011-01-16
DOI:10.3871/j.1004-7220.2011.02.172.
中文关键词:  力学参数  关节软骨  依赖深度变化  两相多孔介质  数值模拟  建模
英文关键词:Mechanical parameters  Articular cartilage  Depth dependent  Biphasic porous media  Numerical simulation  Modeling
基金项目:国家自然科学基金重大国际合作研究项目(30810103908/C100203)
作者单位
周海宇 上海交通大学 机械与动力工程学院 
李元超 上海交通大学 机械与动力工程学院 
王成焘 上海交通大学 机械与动力工程学院 
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中文摘要:
      目的 在软骨数值模拟中,对由于设置均匀和随深度变化的力学参数而导致的结果差异进行评估。方法 利用COMSOL多孔介质模块建立软骨非线性两相多孔介质模型。在静载荷下,分别用均匀和随深度变化的两种软骨力学参数对模型进行了计算,并对两者的计算结果差异进行了分析。结果 对于软骨总应力,两种参数设置的结果之间差异很小。但在分析软骨的固相应力、液体压力和流动等较深入细致的问题时,两种参数设置结果之间的差异不能忽略。结论 不同的软骨力学参数设置对软骨总应力的结果几乎没有影响,但对软骨内流速场则影响很大。所以均匀的力学参数设置可用来简化计算软骨总应力的问题,而其他一些更细致的分析需要立足于随深度变化的软骨力学参数。这些结论可以为今后的软骨建模和数值计算提供参考,为人工关节的设计和计算奠定基础。
英文摘要:
      Objective To evaluate the difference in articular cartilage simulation due to the application of either homogeneous or depth-dependent mechanical parameters. Method The nonlinear, biphasic, porous model of articular cartilage was built using poroelasticity module in COMSOL. Under the static load, the model was computed using homogeneous and depth dependent parameter, respectively. The difference between the results was analyzed. Results For the total stress of cartilage, there was no remarkable difference between two parameter configurations. However, for the analysis such as solid phase stress, fluid pressure and flow velocity, the difference between two parameter configurations must be considered. Conclusions Different parameter configuration has negligible effect on the total stress of cartilage, but it is influential to the flow velocity. Therefore, homogeneous mechanical parameters should be used in order to simplify the total stress computation problem. The other more detailed analysis should be based on the depth dependent parameters. These conclusions could be referred to for future cartilage modeling and numerical computation and thus laying a foundation for the design and computation of artificial joint.
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