Objective This rotated-compression experiment of adult pelvis of wrist cartilage was to provide some relevant evidences to the injury and chronic strain of this configuration, and to prevention and cure of it. Method Histological experiments of pelvis of wrist cartilage of normal adults. Result Regular pelvis of wrist cartilage is fibro cartilage, and the fiber array of all parts in it are different according to various structure functions; also vascular is rich, but no nerve visible. After durative and rotated pressure experiments, tissue cells in pelvis of wrist cartilage were deformed, cartilage lacuna was nearly disappeared, and vascular was injured. Conclusions The histological structure of pelvis of wrist cartilage has functionally adaptation, and ample vascular to provide nutrition. However, excessive load can make histology structure changed, which loses supply of nutrition, and is fatigue injured.