Objective To study the biomechanical characteristics of a new preventslide clavicular nail for treatment of clavicular fracture. This study was made to provide some biomechanical evidences for better clinical operation. Methods 9 adult clavicles were divided into 3 groups randomly, and made a model for the middle and lateral fractures. Those 3 groups was fixed with prevent-slide clavicular nail(PSCN), 4 holes steel plate(4SP) or kirschner's pin(KP), respectively. The biomechanical test was performed and the stress was analyzed. Results (1)Bending strength of internal fixation with 4SP and PSCN were close to normal specimen group(NS) (P>0.05);but KP group was less than normal specimen group (P<0.05).(2) Torsional strength and stiffness of internal fixation with 4SP and PSCN were less than NS group,but more than KP group (P<0.05).(3) Anti-putout strength and stiffness of internal fixation 4SP and PSCN were larger than KP group (P<0.05); Anti-putout power of internal fixation with PSCN were larger than KP group (P<0.05).(4) Stress shielding of internal fixation with PSCP were less than 4SP group (P<0.05). Conclusion The strength and stiffness of PSCN was larger than that of KP,and was close to 4SP.The stress shielding of PSCN was the less.The internal fixation with PSCN is an ideal method for treating clavicular fracture.