Objective The aim of the study is to investigate the Gas-trio antrum motility in healthy subject (HS) and in patients with functional despepsia (FD) and the effect on the motility of massuge therapy and cisapride. Methods 30 HS and 90 FD were studied by detecting Gastric antrun motility. Results the number of MMC for fasting 3 hours is reducedsignificantly and the gastric antrum motility parameters are reduced in patients with FD for postprandial 2 hours as compared to that of controls (P＜0.01, all) After treatment by massage and cisapride, the gastric antrummotility parameters are increased significantly in patients with FD as compared with that before theatment. No significant difference is observed between the above parameters in patients with FD after treatment and before treatment by placebo. Conclusion the massage and cisapride therapy can improve the gastric antrum motility partial patients with FD. these parameters can be put to objetive basis evaluated the effectiveness of the treatment.