眼生物力学2025年研究进展
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天津市眼科医院 南开大学附属眼科医院 天津医科大学眼科临床学院 天津市眼科研究所 天津市眼科学与视觉科学重点实验室

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国家自然科学基金项目(面上项目,重点项目,重大项目)


Research Progress of Ocular Biomechanics in 2025
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Tianjin Eye Hospital, Nankai University Affiliated Eye Hospital, Clinical College of Ophthalmology of Tianjin Medical University, Tianjin Eye Institute, Tianjin Key Laboratory of Ophthalmology and Visual Science

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    摘要:

    眼生物力学作为揭示眼部疾病生理病理力学作用机制的新兴领域,正逐渐受到关注。本文简要概述了2025年一系列新兴眼生物力学测量技术及其研究进展对眼组织力学特性多维度的精准量化,同时展现并强调了人工智能与多模态融合如何作为“加速器”助力临床对眼生物力学作用等。此外,重点回顾了本年度力学因素几个焦点例如在近视、圆锥角膜、青光眼等主要眼病发生发展中的生物学机制研究,为寻找新的干预靶点提供新的角度和思路。未来该领域有望实现从“测量力”到“调控力”的全方位眼生物力学认知,为眼科相关疾病提供全新的解决方案。

    Abstract:

    Ocular biomechanics, an increasingly vital field for elucidating the pathophysiological mechanisms of eye diseases, is garnering increasing attention. This review concisely summarizes a series of novel ocular biomechanical measurement techniques and their research advances in 2025, which enable multi-dimensional and precise quantification of ocular tissue mechanical properties. It also demonstrates and emphasizes how the integration of artificial intelligence with multi-modal data serves as an "accelerator," enhancing the clinical understanding of ocular biomechanical. Furthermore, the review highlights recent key points in exploring the role of mechanical factors in the pathogenesis of major ocular diseases, including myopia, keratoconus, and glaucoma, offering new perspectives for identifying novel interventional targets. In the future, it is expected to evolve from "measuring forces" to "modulating forces," thereby paving the way for innovative therapeutic strategies in ophthalmology.

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  • 收稿日期:2025-11-29
  • 最后修改日期:2025-11-29
  • 录用日期:2025-12-01
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