摘要：目的 研究单髁膝关节置换（UKA）假体不同后倾角度安装对膝关节承载、运动及衬垫磨损的影响。方法 本文联合UKA骨肌多体动力学模型、有限元模型和磨损模型，研究了固定式UKA假体5种后倾角安装位置情况对术后膝关节力和运动、衬垫接触应力、线性磨损深度和体积磨损量的影响。结果 随着UKA胫骨假体后倾角的增加，步态周期内旋运动增大、后移运动增大，摆动相的内侧关节力增大，5百万磨损周期后的衬垫范式等效应力与接触应力显著减小，衬垫的磨损面积、最大线性磨损深度和体积磨损量随之减少。相对于后倾角0°，后倾角为3°、5°、7°时衬垫的线性磨损深度减小了17.8%、19.2%、20.6%；衬垫体积磨损量分别下降了24.5%、30.9%、34.3%。结论 UKA假体考虑后倾角安装超过3°时会显著增加了步态周期内旋运动和后移运动，减小聚乙烯衬垫关节面的磨损。
Abstract: Objective To study the effect of different posterior slope installations of unicompartmental knee arthroplasty (UKA) prosthesis on the knee joint loading, motion and tibial insert wear. Methods This study utilized a combined approach involving UKA musculoskeletal multibody dynamic model, finite element model, and wear prediction model to investigate the effects of five different posterior slope installation position of UKA prosthesis on postoperative knee joint force and motion, insert contact stress, linear wear depth, and wear volume. Results As the posterior slope angle of the UKA prosthesis increased, the internal rotation and posterior translation during the gait cycle increased, the medial joint force during the swing phase increased, the Von Mises stress and contact stress of the insert after 5 million wear cycles decreased significantly, and the wear area, the maximum linear wear depth and the volumetric wear volume of the insert were reduced consequently. Compared with the posterior slope of 0°, the linear wear depths of the insert for the posterior slopes of 3°, 5°, and 7° decreased by 17.8%, 19.2% and 20.6%, respectively; and the volumetric wear volumes of the insert decreased by 24.5%, 30.9%, and 34.3%, respectively. Conclusion Installing UKA prosthesis with a posterior slope exceeding 3° significantly would increase the internal rotation and posterior translation during the gait cycle, further reduce articular volumetric wear of the polyethylene insert .