个体化颈动脉瘤的血流动力学特性分析
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1.新疆大学 机械工程学院;2.新疆医科大学第一附属医院 神经外科 乌鲁木齐

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动脉瘤支架与血流场作用机理及支架的无沉积设计


Analysis of Hemodynamic Characteristics of Individualized Carotid Aneurysms
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1.School of Mechanical Engineering,Xinjiang University,Xinjiang Urumqi;2.Department of Neurosurgery,the First Affiliated Hospital of Xinjiang Medical University

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    摘要:

    摘要:目的 旨在构建个体化的流-固耦合模型,计算分析不同血液特性对动脉瘤腔内血液动力学的影响,进一步探讨对脑动脉瘤破裂的影响。方法 首先采集3D数字剪影图像构建动脉瘤模型,通过流体动力学计算方法(CFD)分析在相同边界条件下,不同血流特性对颈动脉瘤动力学参数的影响。最后对简化颈动脉瘤实验模型进行了PIV实验,以验证血流计算方法的可靠性。结果 不同血流特性的流-固耦合模型,在一个心动周期内,在相同时刻,瘤腔内的低速区域面积、瘤腔流线分布、WSS及动脉瘤壁面变形有较大的差异。通过实验发现在瘤腔内涡流位置随速度变化而变化,与模拟分析结果流动趋势相一致。结论 两种血液特性差异较小,但非牛顿流体更加接近血液真实状态,数值结果将更接近真实流动状态。

    Abstract:

    Abstract: Objective: The aim is to construct an individualized fluid-solid coupling model, calculate and analyze the influence of different blood characteristics on the hemodynamics in the aneurysm cavity, and further explore the influence on the rupture of cerebral aneurysm.. MethodsFirst, 3D digital silhouette images are collected to construct an aneurysm model, and the influence of different blood flow characteristics on the dynamic parameters of carotid aneurysm is analyzed by the fluid dynamic calculation method (CFD) under the same boundary conditions. Finally, a PIV experiment was performed on the simplified carotid aneurysm experimental model to verify the reliability of the blood flow calculation method.Results The fluid-structure coupling model with different blood flow characteristics, within a cardiac cycle, at the same time, there are big differences in the area of low velocity area in the tumor cavity, the streamline distribution of the tumor cavity, WSS and the deformation of the aneurysm wall. Through experiments, it is found that the position of the vortex in the tumor cavity changes with the speed, which is consistent with the flow trend of the simulation analysis result. Conclusion The two kinds of blood characteristics are less different, but the non-Newtonian fluid is closer to the true state of blood, and the numerical result will be closer to the true flow state.

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  • 收稿日期:2020-06-28
  • 最后修改日期:2020-08-12
  • 录用日期:2020-08-24
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