抗反流胆道支架研究现状及进展
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1.天津大学机构理论与装备设计教育部重点实验室;2.天津市南开医院

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国家自然科学基金项目(面上项目,重点项目,重大项目)


A Review of Anti-reflux Biliary Stent
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1.Key Laboratory of Mechanism Theory and Equipment Design of Ministry of Education,Tianjin University;2.Nankai Hospital,Nankai University

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    摘要:

    胆道支架是治疗恶性胆道梗阻的有效手段,而常规胆道支架术后普遍存在肠胆反流,从而引发胆道逆行感染、支架堵塞等并发症,严重降低了患者生存质量。目前抗反流胆道支架被认为是兼顾引流与抑制肠胆反流功能的具有前景的姑息性治疗手段。本文对抗反流胆道支架的研究现状进行了综述,重点对抗反流瓣膜的功能设计与评估、瓣膜与本体支架连接设计、抗反流胆道支架生物力学问题等方面进行了概述总结,并对抗反流胆道支架当前研究进展与趋势进行了总结与分析。

    Abstract:

    Biliary stent is an effective method for malignant biliary obstruction. However, duodenobiliary reflux is common after conventional stent, which causes complications such as biliary retrograde infection and stent blockage, and seriously reduces the quality of patients’ life. At present, anti-reflux biliary stent is considered as a promising palliative treatment method that takes into account drainage and preventing duodenobiliary reflux. In this paper, research status of anti-reflux biliary stent was reviewed, and focus on key problems such as design and evaluation of anti-reflux valve, valve and stent connection design, biomechanical analysis of anti-reflux biliary stent. The current research progress and trend of anti-reflux biliary stent were summarized and analyzed.

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  • 收稿日期:2020-03-05
  • 最后修改日期:2020-04-29
  • 录用日期:2020-05-06
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