穿戴模拟重力服对微重力环境下人腰椎间盘退变影响的生物力学仿真研究
DOI:
作者:
作者单位:

同济大学

作者简介:

通讯作者:

中图分类号:

基金项目:

国家自然科学基金项目(面上项目,重点项目,重大项目)微重力环境致腰椎疾患的生物力学机制及对抗措施的实验及仿真研究


Effect of Gravity Loading Countermeasure Garment on Degeneration of Lumbar Intervertebral Disc under Microgravity Environment: A Biomechanical simulation
Author:
Affiliation:

Tongji University

Fund Project:

  • 摘要
  • |
  • 图/表
  • |
  • 访问统计
  • |
  • 参考文献
  • |
  • 相似文献
  • |
  • 引证文献
  • |
  • 资源附件
  • |
  • 文章评论
    摘要:

    目的:分析微重力环境下穿戴模拟重力服对人腰椎间盘的生物力学效应。方法:基于健康的成年志愿者CT影像,建立人L4-5脊柱单元的有限元模型。在腰椎有限元模型空载荷,以及加载4小时400N轴向载荷基础上,分别模拟微重力环境下无干预和穿戴模拟重力服对腰椎间盘的生物力学效应。结果:微重力环境下,人腰椎间盘中心孔压、径向位移和含水量随时间推移而增大。微重力环境穿戴模拟重力服情况下,72小时后腰椎间盘中心孔压、轴向应力、径向位移和含水量与无干预组相比均有减小。结论:微重力环境可能会导致人腰椎间盘退变,穿戴模拟重力服可以在一定程度上可帮助宇航员对抗微重力造成的对脊柱的不利影响。

    Abstract:

    Objective: To analyze the biomechanical effects of gravity loading countermeasure garment on human lumbar intervertebral disc under microgravity environment. Methods: Based on CT images of a healthy adult volunteer, the finite element model of L4-5 spinal unit was established. Through the empty load and loading of 400N axial load for 4 hours on lumbar finite element model, the biomechanical effect of the non-intervention and gravity loading countermeasure garment were simulated respectively under microgravity environment. Results:, The central pore pressure, radial displacement and water content of the human lumbar intervertebral disc increased with time under microgravity environment. In the case of wearing gravity loading countermeasure garment, the central pore pressure, axial stress, radial displacement and water content of the lumbar intervertebral disc were reduced after 72 hours of cyclic loading compared with the non-intervention group. Conclusions: The microgravity environment may cause degeneration of the lumbar intervertebral disc. Wearing gravity loading countermeasure garment can help the astronauts to prevent the adverse effects of the microgravity on the spine to some extent.

    参考文献
    相似文献
    引证文献
引用本文
分享
文章指标
  • 点击次数:
  • 下载次数:
  • HTML阅读次数:
  • 引用次数:
历史
  • 收稿日期:2019-09-10
  • 最后修改日期:2019-11-13
  • 录用日期:2019-11-19
  • 在线发布日期:
  • 出版日期: