Abstract:Objective A comprehensive consideration of therapeutic effect on tumors and its branches with Flow Diverter(FD) implantation is conducive to make a more reasonable surgical strategy for intracranial aneurysm embolization in clinical practice. Methods Based on computational fluid dynamics(CFD) technique, our paper simulated FD implantation procedure using porous media model innovatively. Results FD changed the hemodynamic characteristics of aneurysms. Specifically, when FD was implanted, the blood velocity decreased, the wall pressure on tumor roof also decreased significantly, while the wall shear stress(WSS) on aneurysmal neck increased, inversely, the difference between proximal and distal cervical area reduced. What is more, different side branch vessels have different effects on hemodynamic characteristic changes. When branching diameters were larger, the blood flow reduction in themselves after FD implantation was greater, but the velocity in tumor and the pressure on aneurysmal roof were smaller simultaneously. Meanwhile, the increment of WSS on aneurysmal neck was inversely proportional to the side branch diameter. Conclusion Under the circumstance of thicker side vessels, FD interventional treatment should be paid more attention by clinicians, on account of worse embolization、worse atherosclerosis improvements and more possibilities of branch occlusion or other ischemic complications.