1.Hebei University of Technology,State Key Laboratory of Reliability and Intelligence of Electrical Equipment and Hebei Key Laboratory of Robot sensing and Human-robot Interaction,Tianjin,300130;2.P.R. China
目的 开发一种适用于日常居家使用的无束缚睡眠呼吸监测方法，实现睡眠呼吸暂停综合征（Sleep Apnea Syndrom，SAS）及呼吸系统疾病的无束缚筛查。方法 提出了一种基于床单式柔性压力传感器的无束缚胸腹呼吸监测方法，通过检测呼吸时胸部和腹部作用于床垫的动态压力获取呼吸信息。对10名健康受试者进行了无束缚监测与胸腹呼吸带监测的对比实验，验证了所提出方法的有效性。结果 床单式柔性压力传感器可以检测呼吸时胸部和腹部作用于床垫的动态压力，并据此获取呼吸波形和呼吸率信息，其中，呼吸率与胸腹呼吸带的输出结果相同，但呼吸波形与胸腹呼吸带输出信号在相位上存在差异，该差异与受试者的睡姿和性别有关：对于仰卧位或侧卧位的男性受试者，胸部的动态压力与胸部呼吸带输出信号相位相反，腹部的动态压力与腹部呼吸带输出信号相位相同；对于仰卧位的女性受试者，胸部与腹部的动态压力变化同相位，并且与胸腹呼吸带的输出信号同相位；对于侧卧位的女性受试者胸部的动态压力与胸部呼吸带输出信号相位相同，但腹部的动态压力与腹部呼吸带输出信号相位相反。结论 床单式柔性压力传感器可以无束缚监测呼吸时胸部和腹部运动，具有判别睡眠呼吸暂停综合征类型的潜力，但胸腹运动存在力学耦合关系，欲利用动态压力识别胸腹运动的相位差，需进行解耦研究。
Objective Develop an unconstrained sleep respiration method suitable for daily use at home to realize high precision screening of sleep apnea syndrome or other respiratory diseases without affecting normal sleep. Methods A new unconstrained measurement method using sheet-type flexible pressure sensor was proposed. This method obtains the information of respiratory motions of chest and abdomen by measuring the pressure fluctuations of the chest and abdomen acting on the mattress. The experiments were conducted on ten healthy subjects to confirm the effectiveness of the proposed method by comparing the results of the unconstrained measurement and those of respiratory inductance plethysmography (RIP) using band sensors. Results Sheet-type flexible pressure sensor could measure the pressure fluctuations of the chest and abdomen acting on the mattress during respiration and obtain respiratory waveform and respiratory rate. The respiratory rate measured with the sheet-type flexible pressure sensor agreed with those obtained by RIP. However, it was interesting to find that the gender and the lying position greatly affect whether the phases of the motions of the chest and abdomen measured with the flexible sensor differed from those obtained by RIP. For male subjects in supine or lateral lying positions, the pressure fluctuation originating from the motion of the abdomen was in-phase with the output of the abdomen band sensor, while that from the chest was out-of-phase with the output of the chest band sensor. For female subjects in a supine lying position, the pressure caused by the motion of the chest in-phase fluctuated with that of the abdomen; both of these outputs were in-phase with the output of the band sensors. In the case of female subjects in a lateral lying position, the pressure fluctuation from the chest and that from the abdomen were out-of-phase, and the pressure fluctuations of the chest and abdomen were in- and out-of-phase compared to those of the outputs of the band sensors, respectively. Conclusions Sheet-type flexible pressure sensor is effective to monitor unconstraint sleep respiration; this indicates the potential to identify the types of sleep apnea syndrome. But further researches are required to identify the phase difference between the motion of chest and the abdomen, which are coupled with each other.