1.China University of Mining and Technology;2.The Affiliated Hospital of Xu Zhou Medical University
目的 研究中耳畸形对圆窗激振性能的影响,为圆窗激振式人工中耳的优化提供理论支持。方法 构建包含两腔不对称的非螺旋耳蜗的人耳有限元模型,并与实验数据进行对比,验证模型的可靠性。基于该模型,通过改变相应组织的材料属性,分别模拟听骨链固定、听骨链融合、听小骨缺损这三种中耳畸形对圆窗激振性能的影响。结果 中耳畸形主要影响圆窗激振式人工中耳的低频性能,听骨链固定和听骨链融合对圆窗激振起恶化效果,其中,镫骨固定对圆窗激振补偿性能的恶化最大；听小骨缺损可提高圆窗激振的性能。结论 中耳畸形对圆窗激振的低频性能有影响,临床植入圆窗激振式人工中耳时需要针对性地提高其作动器的输出量。
Objective To study the influence of middle ear malformation on the performance of round window stimulation, and provide reference for the optimization of round window stimulation middle ear implant. Methods A human ear finite element model including an asymmetrical two-cavity non-helical cochlea was constructed and compared with experimental data to verify the reliability of the model. Based on the model, the effects of three kinds of middle ear malformations,i.e., ossicular chain fixation, ossicular chain fusion and ossicular defect on the round window stimulation were simulated by changing the material properties of the corresponding tissues. Results The middle ear malformation mainly affects the low-frequency performance of the round window stimulation. The ossicular chain fixation and the ossicular chain fusion have a deteriorating effect on the round window stimulation. Among them, the stapes fixation has the greatest deterioration of the round window stimulation’s performance. Ossicles defects can boost the performance of round window stimulation. Conclusions The middle ear malformation has an effect on the low frequency performance of the round window stimulation. When designing the round window stimulation type middle ear implant, it is necessary to increase the output of its actuator accordingly.