Objective Developed a new electric stapler to improve the automation, convenience and precision of minimally invasive surgery. Methods The clamping, firing and turning mechanism of the new electric stapler was innovatively designed to realize the electric drive of minimally invasive surgical anastomosis on the basis of traditional mechanical stapler. The motion process of electric clamping, firing and double-screw turning mechanism is analyzed in detail, and the equations of motion function of three mechanisms are solved, which provides a theoretical basis for the intelligent control algorithm of electric stapler. Results The electric clamping and firing process was simulated using ADAMS software to verify the equation of motion. The prototype of the new electric stapler was made, and the anastomosis experiment and blasting pressure experiment of the ex vivo small intestine tissue were carried out. The value of anastomotic blasting pressure was between 3.7 kPa and 11.67 kPa, which met the basic clinical requirements. Conclusions The structure of the new electric stapler can meet the requirements of electric pressing and firing in minimally invasive surgery, which can help doctors to achieve tissue anastomosis more conveniently, quickly and effectively.