目的 为满足健康监护中的连续测量血压的要求，研究并实现一种基于脉搏波信号和血管弹性腔模型的动脉血压拟合计算方法。方法 利用自制的穿戴式人体生理参数监测系统收集测试对象的脉搏波信号、心电信号以及血压数据。根据心电信号与脉搏波信号的时间关系，推导出收缩压和脉搏波传导时间的回归分析方程，而舒张压的测量，则是通过脉搏波的波形系数分析以及血管单弹性腔模型的参数计算完成。结果 试验结果表明，该方法血压测量结果的平均偏差和标准偏差为（0.51±0.74) kPa［(384±5.54) mmHg］，达到了美国医疗仪器促进协会建议的(0.665±1.064) kPa［(5±8) mmHg］标准。 结论 结合脉搏波信号和弹性腔模型可以估算人体血压值，为连续血压测量提供了新的实现方法。
Objective An arterial blood pressure fitting method, based on pulse wave signal and vessel elastic chamber model, was researched and implemented to meet the requirement of continuous blood pressure (BP) measurement in health care. Methods Photoplethysmography (PPG) signal, electrocardiograph (ECG) signal and BP data of the subjects were collected by a self developed wearable physiological monitoring system. In accordance with the temporal relation between ECG and PPG signals, the equation of regression analysis on systolic BP value and pulse wave transient time (PWTT) was deduced, and the diastolic BP measurement was achieved by coefficients analysis on PPG wave and parameter calculation on blood vessel single elastic chamber model. Results The experiment results showed that the mean difference and the standard deviation of the method were （0.51±0.74) kPa［(384±5.54) mmHg］, reaching the standard (0.665±1.064) kPa［(5±8) mmHg］ proposed by Association for the Advancement of Medical Instrumentation (AAMI). Conclusions Human blood pressure can be estimated by the pulse wave signal and elastic chamber model, which provides a new method for the continuous blood pressure measurement.