鼻腔气道结构对鼻腔加温加湿功能影响的数值模拟
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国家自然科学基金资助项目(10902022,10872043),大连理工大学科研启动经费项目


Numerical simulation for the influence of nasal cavity structure on nasal function of warming and humidifying the inhaled airflow
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    摘要:

    目的 研究鼻腔气道结构的变化对鼻腔加温加湿功能的影响。方法 选取9例正常人和2例鼻中隔偏曲患者(术前术后)作为研究对象,建立鼻腔的三维有限元模型,数值模拟鼻腔气道中的气流分布、气流温度和湿度,并对比正常人与病患、术前与术后的数值模拟结果。结果 鼻腔气道宽敞一侧气流体积流率相对较大,加温加湿效果差;狭窄一侧加温效果相对较好。对于正常人,鼻腔对吸入气流加温加湿的部位主要位于前端;对于病患,则要取决于鼻腔的气道结构。结论 鼻腔气道结构影响鼻腔对吸入气流的加温加湿效果,鼻腔气道结构的几何参数如鼻腔气道壁面积、鼻腔体积可以用来衡量鼻腔对气流的加温加湿效果。

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    Objective To study the influence of nasal cavity structure on nasal function of warming and humidifying the inhaled airflow. Method Nine normal persons and two patients with deviation of nasal septum (pre and postoperation) were selected as research subjects. The threedimensional finite element model of nasal cavities of these volunteers was established. Numerical simulations for the airflow distribution, the airflow temperature and the airflow humidity in the nasal cavity were performed. Based on the simulation results, comparisons were made between normal nasal cavities and the patient’s nasal cavities as well as between the pre-and post-operative nasal cavities. ResultsIn the wider side of nasal cavity, the volume flow rate and the velocity of airflow were higher and the effect of warming and humidifying on the airflow was worse. For normal people, the nasal cavity for warming and humidifying the inhaled airflow was in the anterior segment of the nose. While for the patients, the main segment of warming and humidifying the inhaled airflow had to depend on the airway geometry. Conclusions The nasal cavity structure can influence the effect of warming and humidifying on the airflow. The parameters describing the geometry of nasal cavity, such as the surface area of nasal airway and volume of nasal cavity, may be a useful measurement for the nasal function of warming and humidifying the inhaled airflow.

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于申,刘迎曦,孙秀珍,苏英锋.鼻腔气道结构对鼻腔加温加湿功能影响的数值模拟[J].医用生物力学,2010,25(6):444-448

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  • 收稿日期:2010-07-29
  • 最后修改日期:2010-09-10
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